SLC2A14 In Hepatoblastoma Clinical Significance And Potential Roles In Ferroptosis

Authors

  • Wen Bing Li Department of Hepatobiliary Surgery, The Cancer Hospital of Guangxi Medical Universit Author
  • Jing Xiao Li Department of Thoracic Surgery, The First Affiliated Hospital of Guangxi Medical University Author
  • Guo Sheng Li Department of Hepatobiliary Surgery, The Cancer Hospital of Guangxi Medical University Author
  • Gui Yu Feng Department of Hepatobiliary Surgery, The Cancer Hospital of Guangxi Medical University Author
  • Guan Qiang Yan Department of Hepatobiliary Surgery, The Cancer Hospital of Guangxi Medical University, Author
  • Xiang Gao Department of Hepatobiliary Surgery, The Cancer Hospital of Guangxi Medical University, Author
  • Jun Liu Department of Cardiothoracic Surgery, The First Affiliated Hospital of Guangxi Medical University Author
  • Hua Fu Zhou Department of Cardiothoracic Surgery, The First Affiliated Hospital of Guangxi Medical University Author

DOI:

https://doi.org/10.70731/m43vmz32

Keywords:

Hepatoblastoma,SLC2A14,Ferroptosis,GLUT Family,Pediatric Oncology,Tumor Metabolism

Abstract

The study aimed to investigate the role of SLC2A14 in hepatoblastomaHB,a prevalent pediatric liver tumor.Through RNA-seq analysis of public and in-house datasets,we found SLC2A14 upregulated in HB and linked to ferroptosis.Our analysis revealed SLC2A14s potential as a diagnostic marker and its association with tumor metabolism,suggesting it may be a therapeutic target.The study concludes that SLC2A14s role in HB should be further explored for clinical applications.

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Published

16.01.2025

Issue

Vol. 1 No. 1 (2025): Volume 1, Number 1

Section

Articles

How to Cite

SLC2A14 In Hepatoblastoma Clinical Significance And Potential Roles In Ferroptosis. (2025). International Journal of Clinical Medicine and Pharmacology, 1(1). https://doi.org/10.70731/m43vmz32