The essence of technology is at the same time the essence of man. Ernst Karp and Karl Marx are great philosophers in the same period, who successively formed a distinctive philosophy of technology and view of technology in their understanding of the concept of technology in terms of technological ontology, technological evolution and society, culture and state. On the basis of analyzing and comparing the differences between Karp’s and Marx’s views on technology in terms of technological ontology and technological epistemology, this paper follows the dialectical way of thinking and finds that Karp’s view of technology is narrow in terms of the existence of isolation and mechanicity. Marx’s view of technology, on the other hand, explains the relationship between society, technology, and productive forces in a discourse led by holistic thinking, and ultimately puts human beings in the link of purpose and power of technological development for dynamic examination.