Volume 1, Number 1

Published: 16 January 2025

  • Research article
    Pages
    1-13

    SLC2A14 In Hepatoblastoma Clinical Significance And Potential Roles In Ferroptosis

    Wenbing Li
    ,
    Jingxiao Li
    ,
    Guosheng Li
    ,
    Guiyu Feng
    ,
    Guanqiang Yan
    The study aimed to investigate the role of SLC2A14 in hepatoblastoma (HB), a prevalent pediatric liver tumor.Through RNA-seq analysis of public and in-house datasets,we found SLC2A14 upregulated in HB and linked to ferroptosis.Our analysis revealed SLC2A14s potential as a diagnostic marker and its association with tumor metabolism,suggesting it may be a therapeutic target.The study concludes that SLC2A14s role in HB should be further explored for clinical applications.
  • Research article
    Pages
    14-26

    Global Trends and Hotspots in Tongue Cancer Research:A Bibliometric Analysis (2014-2024)

    Xin Meng
    ,
    Jingrui Zhang
    ,
    Yongjie Guo
    ,
    Jun Ma
    ,
    Xinyu Li
    This study conducts a bibliometric analysis of 1,553 tongue cancer-related publications from 2014 to 2024, sourced from the Web of Science database, to uncover global research trends, hotspots, key contributors, and future directions in the field. Results indicate a significant rise in research activity, with China, the United States, and Japan leading in output and international collaboration. Emerging hotspots include the use of advanced technologies such as artificial intelligence, deep learning, and radiomics for early diagnosis, prognostic evaluation, and treatment, as well as a growing focus on younger patient populations and immunotherapy strategies. Future research should emphasize interdisciplinary collaboration, integrating bioinformatics, imaging, and clinical studies, while fostering international cooperation and data sharing to advance understanding of tongue cancer pathogenesis and improve treatment outcomes, survival rates, and quality of life for patients.
  • Research article
    Pages
    27-35

    Two Cases of Maxillofacial Vascular Malformations Associated with Blue Rubber Bleb Nevus Syndrome And Literature Review

    Xin Meng
    ,
    Yongjie Guo
    ,
    Jingrui Zhang
    ,
    Jun Ma
    ,
    Xinyu Li
    Blue Rubber Bleb Nevus Syndrome (BRBNS) is a rare systemic vascular malformation-related disorder that primarily affects the skin, gastrointestinal tract, and central nervous system. Approximately 55.9% of patients have lesions involving the oral and maxillofacial region. Due to the potential risks of gastrointestinal hemorrhage and intracerebral hemorrhage, it is crucial for dental practitioners to promptly identify and refer such cases to relevant departments to improve patient prognosis and enhance quality of life. This paper reports two cases of BRBNS associated with maxillofacial vascular malformations treated at the Oral and Maxillofacial Surgery Department of Henan Provincial People’s Hospital. In conjunction with a literature review, this study discusses the clinical features, diagnosis, and treatment strategies of BRBNS, aiming to raise awareness among dental practitioners to avoid missed or incorrect diagnoses.
  • Research article
    Pages
    36-40

    The efficacy and safety of acupoint application for cirrhotic ascites: A protocol for systematic review and meta-analysis

    Xiaoying Yao
    ,
    Liuping Zhang
    ,
    Yulan Gao
    ,
    He Li
    ,
    Fangyu Long
    Cirrhotic ascites significantly impacts patients’ quality of life and poses serious clinical challenges. Conventional treatments, such as diuresis and abdominocentesis, are costly and prone to recurrence. Acupoint application, a traditional Chinese medicine (TCM) external therapy, offers a safe, painless, and cost-effective alternative widely used in clinical practice. However, its efficacy and safety lack systematic evaluation. This study aims to comprehensively assess the effectiveness and safety of acupoint application for treating cirrhotic ascites through a meta-analysis of randomized controlled trials retrieved from databases including CNKI, VIP, WanFang, PubMed, Embase, and the Cochrane Library. The findings will provide evidence to guide clinical decision-making.

  • Research article
    Pages
    41-51

    Advances in Personalized Diagnosis and Treatment Strategies for Temporomandibular Disorders

    Jingrui Zhang
    ,
    Xin Meng
    ,
    Ke Xu
    ,
    Jun Ma
    ,
    Xinyu Li
    Temporomandibular joint disorders (TMDs) is a broad term encompassing pain and/or functional impairment of the masticatory muscles and the temporomandibular joint. Currently, the clinical treatment principles for TMDs mainly include etiological treatment and symptomatic treatment. In addition, the development of personalized diagnostic and treatment plans is crucial for the effective management of TMDs. This review systematically outlines the patient intake process for TMDs and discusses the importance and methods of developing personalized etiological and symptomatic treatment plans based on patient characteristics such as age and symptoms, aiming to provide clinical practitioners with guidance on patient management.
  • Research article
    Pages
    52-56

    Clinical Research and Mechanism Exploration of Moxibustion in Promoting Children’s Growth and Development 

    Xize Sun
    ,
    Ximan Sun
    To evaluate the effect of moxibustion on children’s growth and development and explore its underlying mechanisms. A total of 60 children with growth and development retardation were randomly divided into a moxibustion treatment group and a control group. The treatment group received moxibustion at specific acupoints, while the control group received no intervention. The height, weight, and bone age of the children were measured before and after treatment, and relevant hormones and growth factors were detected. After treatment, the height, weight, and bone age of the children in the moxibustion treatment group were significantly improved compared with those in the control group. The levels of growth hormones and insulin-like growth factor-1 in the treatment group were also significantly increased. Moxibustion can effectively promote children’s growth and development, and its mechanism may be related to the regulation of growth hormones and growth factors.