Research article
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DOI:
https://doi.org/10.70731/m43vmz32

SLC2A14 In Hepatoblastoma Clinical Significance And Potential Roles In Ferroptosis

Wenbing Li
,
Jingxiao Li
,
Guosheng Li
,
Guiyu Feng
,
Guanqiang Yan
,
Xiang Gao
,
Jun Liu
,
Huafu Zhou

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International Journal of Clinical Medicine & Pharmacology – Volume 1, Number 1

, pages
1-13
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Abstract

The study aimed to investigate the role of SLC2A14 in hepatoblastoma (HB), a prevalent pediatric liver tumor.Through RNA-seq analysis of public and in-house datasets,we found SLC2A14 upregulated in HB and linked to ferroptosis.Our analysis revealed SLC2A14s potential as a diagnostic marker and its association with tumor metabolism,suggesting it may be a therapeutic target.The study concludes that SLC2A14s role in HB should be further explored for clinical applications.

Keywords

Hepatoblastoma
SLC2A14
Ferroptosis
GLUT Family
Pediatric Oncology
Tumor Metabolism

Author’s information

Wenbing Li
Department of Cardiothoracic Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China
Jingxiao Li
Department of Thoracic Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China
Guosheng Li
Department of Cardiothoracic Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China
Guiyu Feng
Department of Cardiothoracic Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China
Guanqiang Yan
Department of Cardiothoracic Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China
Xiang Gao
Department of Cardiothoracic Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China
Jun Liu
Department of Cardiothoracic Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China
Huafu Zhou
Department of Cardiothoracic Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China

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About the article

Wenbing Li, Jingxiao Li, Guosheng Li, Guiyu Feng, Guanqiang Yan, Xiang Gao, Jun Liu, & Huafu Zhou. (2025). SLC2A14 In Hepatoblastoma Clinical Significance And Potential Roles In Ferroptosis. International Journal of Clinical Medicine & Pharmacology, 1(1), 1-13. DOI: https://doi.org/10.70731/m43vmz32

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2025
The Author(s). Published by Jandoo Press.

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